That or Methamphetamine mainly, most likely

top causes, not factors

if your R&D costs make your business unprofitable, something’s going to come along and topple it, same as how “smoking” isn’t a cause of death but lung cancer is a very major cause of death

if you’re British, maps.nls.uk is fascinating for seeing places evolve over time

Is guys really needed after youse?

The guys is needed where there’s no 2.pl pronoun to distinguish from individual you, but youse fixes that